Top Santé: How is irritable bowel syndrome (IBS) currently treated?
Professor Jean-Marc Sabate: Its treatment is complex, since this disorder results from several mechanisms that vary from one patient to another (excessive or insufficient intestinal contractions, hypersensitivity of the digestive tract, stress, etc.). So you have to try different strategies. In general, first-line treatment is based on dietary and lifestyle measures (physical activity, low-FODMAP diet if necessary, etc.), probiotics, and “symptomatic” treatments aimed at reducing the main symptoms: antispasmodics in case of digestive spasms (Spasfon Lyoc®, Météospasmyl®…), laxatives for IBS with constipation (Transipeg®, Forlax®…), antidiarrheals for IBS with diarrhea (Imodium®, Questran®…), etc. . In case of failure, hypnosis has proven its effectiveness: improvement of 50 to 60% of patients who do not respond to the drugs mentioned.
Top Santé: What are the most recent advances?
Pr J.-MS: Several symptomatic treatments have come along in the last ten years, which has been good news for patients who do not respond to any of the conventional treatments mentioned above. In particular, since 2019 Colpermin®, based on mint oil, has been available to treat intestinal hyperactivity, and Gelsectan®, composed of a probiotic and a (…)
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